Granzymes in cancer and immunity
نویسندگان
چکیده
منابع مشابه
A novel role for granzymes in anti-tumor immunity
The cytotoxic properties of granzymes are well established, though recent publications suggest additional roles for granzymes in immunity. We demonstrated that granzymes can act as regulators of cross-presentation by dendritic cells by inducing critical "eat-me" signals on the dying tumor cell, resulting in efficient phagocytosis of cell-associated tumor antigen.
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ژورنال
عنوان ژورنال: Cell Death & Differentiation
سال: 2010
ISSN: 1350-9047,1476-5403
DOI: 10.1038/cdd.2009.206